Signs of a Healthy Chameleon:

A healthy chameleon should be active in its environment and standing up rather than lying on its perch.
The chameleon should be able to move about the cage with good balance without falling or stumbling.
The eyes should be full, open at all times and actively looking all around.
The arm and leg bones should all be straight, toes should all be intact and the chameleon should have a strong grip.
The chameleon’s skin should have vibrant coloration all over the body and all the spines on the back should be present.
Patches of shedding skin should be normal if present.
The tail should be able to grasp branches and curl up smoothly.

Signs of an Unhealthy Chameleon:

A chameleon that sleeps during the day.
It has sunken or swollen eyes.
If it is lying on the bottom of the cage.
Legs that are bent, curved, appear to have multiple joints or have swellings at the joints.
Wrinkly, crusty or dry skin, bumps, cuts or bruises, or patches of abnormal colored skin.
Blood at the mouth, swollen jaw, or jaw that doesn’t align properly.
A tail that cannot curl or is black at the end.
If your chameleon is falling off branches, having a weak grip, stumbling or appearing very clumsy.